약학대학 - 약학대학
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- espark@skku.edu
- 약학관 6층 530638호실
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관심분야
Gastro drug delivery system Controlled release orally disintegrating system Granulation technology Transdermal delivery system Scale-up study Continuous process
학력
- (Ph.D.) Medical University of South Carolina (Physical Pharmacy)
약력/경력
- 1996 - 1999 : School of Pharmacy, Sungkyunkwan University (Assistant Professor)
- 2000 - 2005 : School of Pharmacy, Sungkyunkwan University (Associate Professor)
- 2006 - Present : School of Pharmacy, Sungkyunkwan University (Professor)
- 2008 - 2011 : School of Pharmacy, Sungkyunkwan University (Dean)
- 2016 - Present : Korean Society of Pharmaceutical Sciences and Technology (President)
학술지 논문
- (2022) Complexation of levocetrizine with ion-exchange resins and its effect on the stability of powder mixture containing levocetrizine and montelukast. JOURNAL OF PHARMACEUTICAL INVESTIGATION.
- (2022) Solid-state characterization and amorphous form identification in a small molecule. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY. 147, 11
- (2022) A formulation development strategy for dual-release bilayer tablets: An integrated approach of quality by design and a placebo layer. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 618, 1
- (2022) Development of self-microemulsifying tablets containing dutasteride for enhanced dissolution and pharmacokinetic profile. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 618, 1
- (2022) Formulation of sustained-release orodispersible film containing drug-resin complexes of donepezil hydrochloride. JOURNAL OF PHARMACEUTICAL INVESTIGATION. 52, 2
- (2021) Enhanced permeability and oral absorption of Panax notoginseng saponins by borneol. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 66, 1
- (2021) Novel composite double-layered dressing with improved mechanical properties and wound recovery for thermosensitive drug, Lactobacillus brevis. COMPOSITES PART B-ENGINEERING. 225, 1
- (2021) Effect of gastric residence time on the oral absorption of rebamipide sustained-release tablets in beagle dogs. JOURNAL OF PHARMACEUTICAL INVESTIGATION. 51, 6
- (2021) Development of a Robust Control Strategy for Fixed-Dose Combination Bilayer Tablets with Integrated Quality by Design, Statistical, and Process Analytical Technology Approach. PHARMACEUTICS. 13, 9
- (2021) Utilization of a compaction simulator to formulate mini-tablets containing high dose of acyclovir. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 64, 1
- (2021) Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways. BIOMOLECULES. 11, 7
- (2021) Inhaled bosentan microparticles for the treatment of monocrotaline-induced pulmonary arterial hypertension in rats. JOURNAL OF CONTROLLED RELEASE. 329, 1
- (2020) Anti-obesity effect with reduced adverse effect of the co-administration of mini-tablets containing orlistat and mini-tablets containing xanthan gum: In vitro and in vivo evaluation. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 591,
- (2020) Hair Growth Effect of Emulsion Extracted Brevilin A, a JAK3 Inhibitor, from Centipeda minima. PROCESSES. 8, 7
- (2020) Investigation of critical factors affecting mechanical characteristics of press-coated tablets using a compaction simulator. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 582, 1
- (2020) Preparation and characterization of metformin hydrochloride controlled-release tablet using fatty acid coated granules. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. 46, 5
- (2020) Effects of process parameters of rotary tablet press on die filling behavior during mini-tablet production: Comparison with conventional tablet. POWDER TECHNOLOGY. 362, 1
- (2020) Systematic approach to elucidate compaction behavior of acyclovir using a compaction simulator. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 575, 1
- (2020) Development of novel bilayer gastroretentive tablets based on hydrophobic polymers. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 574, 1
- (2019) Swellable and porous bilayer tablet for gastroretentive drug delivery: Preparation and in vitro-in vivo evaluation. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 572, 1
단행본
- (2011) 마틴의 물리약학. 신일북스. 공동
- (2000) 약사법규. 학창사. 공동
- (1999) 藥事法規. 學窓社. 공동
특허/프로그램
- 다공성 위체류층을 포함하는 서방성 제제 및 이의 제조방법. 10-2018-0040904. 20191112. 대한민국
- 트리암시놀론아세토니드함유구강점막부착제. 0299231. 20010607. 대한민국
- 용출률이 향상된 비페닐디메칠디카르복실레이. 154612. 19980710. 대한민국
수상/공훈
- 수상
- Contribution Award from Korean-American Pharmaceutical Scientists Association (2013)
- Academic Prize from The Korean Society of Pharmaceutical Sciences and Technology (2012)
- Academic Prize from The Pharmaceutical Society of Korea (2009)
- Academic Prize from The Korean Federation of Science and Technology Societies (2009)
학술회의논문
- (2022) Study for the development of predictive model through the correlation between process parameters and response values in continuous process. 2022년 한국약제학회 학술대회. 대한민국
- (2021) Development of sustained-release orodispersible film of memantine hydrovhloride based on drug-resin complex. 2021 한국약제학회 국제학술대회. 대한민국
- (2021) Recent Advances in Gastroretentive Drug Delivery Systems. 2021 한국약제학회 국제학술대회. 대한민국
- (2021) A study on dry particle coating with fumed silica using conical mill for direct compression. 2021 대한약학회 춘계국제학술대회. 대한민국
- (2020) Development of sustained-release microparticles containing ropinirole hydrochloride for orally disintegrating tablet. 2020 대한약학회 추계학술대회. 대한민국
- (2019) Solid-state characterization and amorphous-state identification in a small molecule. 2019 International Conference of The Korean Society of Pharmaceutical Sciences and Technology. 대한민국
- (2019) Development of sustained-release microparticles containing donepezil hydrochloride using drug-ion exchange resin complexes. 2019 International Conference of The Korean Society of Pharmaceutical Sciences and Technology. 대한민국
- (2019) Application of fines recycling process during roller compaction. Application of fines recycling process during roller compaction. 대한민국
- (2019) Comparison of die filling behavior on rotary tablet press between conventional tablet and microtablet. 2019 Fall International Convention of The Pharmaceutical Society of Korea. 대한민국
- (2019) A study on dry granulation formulation for poorly soluble drugs using compaction simulator. 2019 9th AASP Conference. 대한민국
- (2019) Recent Trends in Gastroretentive Drug Delivery Systems. 2019 KJYSP(한일젊은과학자) conference. 일본
- (2018) Design of bilayer gastroretentive tablets containing rebamipide. 2018 한국약제학회 국제학술대회. 대한민국
- (2018) Highly porous bilayer tablets for enhanced gastroretentive properties and easy formulation development. 2018 AAPS Annual Meeting. 미국
- (2018) Influence on granule properties with variable particle size of excipients on twin screw granulation process. 2018 AAPS Annual Meeting. 미국
- (2018) Preparation and evaluation of celecoxib ternary solid dispersion granules using solvent evaporation based one-pot process. 2018 AAPS Annual Meeting. 미국
- (2018) Studies for the demonstration of bioequivalence of various dosage forms. 2018 추계 대한약학회 국제학술대회. 대한민국
- (2018) Optimization of process parameters for active coating system using design of experiment. 2018 춘계 대한약학회 국제학술대회. 대한민국
- (2018) Preparation of active coating suspension containing atorvastatin calcium. 2018 춘계 대한약학회 국제학술대회. 대한민국
- (2017) Development of celecoxib solid dispersion granules by a solvent based one-pot process. 2017 International Conference of The Korean Society of Pharmaceutical Sciences and Technology. 대한민국
- (2017) Understanding Mechanical Properties of High Drug-Loaded Microgranules Using Two Methods. 2017 AAPS Annual Meeting and Exhibition. 미국